Two airplane stowaways are brought into the hospital after suffering major injuries from the travel, prompting Sharon Goodwin to receive a visit from the Department of Homeland Security regarding the undocumented immigrants. Cornelius Rhodes, the wealthy father of Dr. Connor Rhodes, is honored after making a big donation to the hospital for a new psych ward, forcing dark family secrets to the surface. Dr. Natalie Manning's big day arrives and Dr. Will Halstead's good intentions to help are misconstrued by her mother-in-law, Helen. Meanwhile, Dr. Sarah Reese asks Dr. Charles for advice on how to deliver heartbreaking news to a young boy while also warning his family about the possibility that their other son may also have the same life-threatening disease.
